Bioreactors: Animal Cell Culture Control for Bioprocess by Goutam Saha,Alok Barua,Satyabroto Sinha PDF

By Goutam Saha,Alok Barua,Satyabroto Sinha

ISBN-10: 1138749680

ISBN-13: 9781138749689

Bioreactors: Animal mobile tradition keep watch over for Bioprocess Engineering offers the layout, fabrication, and regulate of a brand new kind of bioreactor intended specially for animal mobilephone line tradition. the recent bioreactor, referred to as the "see-saw bioreactor," is perfect for the expansion of cells with a delicate membrane. The see-saw bioreactor derives its identify from its precept of operation during which liquid columns in both limb of the reactor alternately move up and down. The operating quantity of the reactor is small, to inside of 15 L. besides the fact that, it might simply be scaled up for big creation in quantity of phone mass within the drug and pharmaceutical industries.

The authors describe the primary of operation of the see-saw bioreactor and the way to immediately keep watch over the bioprocess. They talk about diverse keep an eye on recommendations in addition to the thorough experimental study they performed in this prototype bioreactor within which they utilized a time hold up regulate for yield maximization.

To offer you a whole knowing of the layout and improvement of the see-saw bioreactor, the authors conceal the mathematical version they use to explain the kinetics of fermentation, the genetic algorithms used for deriving the optimum time trajectories of the bioprocess variables, and the corresponding keep an eye on inputs for maximizing the product yield. One bankruptcy is dedicated to the applying of time hold up keep watch over. Following an outline of the bioreactor’s operating setup within the laboratory, the authors sum up their research and outline the long run scope of labor by way of layout, keep watch over, and software program sensors.

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Bioreactors: Animal Cell Culture Control for Bioprocess Engineering by Goutam Saha,Alok Barua,Satyabroto Sinha

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